Course Director: David Mann, Ph.D.
Biochemistry is the science concerned with cellular constituents
at the molecular level and all the reactions that take place within
a living cell. A biochemical understanding of molecular and cellular
components in health enables physicians to appreciate how the properties
and function of these components are altered in disease. Biochemistry
is fundamental to understanding all branches of the life sciences.
The course is offered during the first two terms of medical school
and is composed of both lectures and workshops. Workshops are conducted
with small groups using case-based learning to illustrate the application
of biochemical concepts in a clinical setting.
BIOC 1511 Biochemistry I
This course features modules on protein structure and enzymes emphasizing
structure-function relationships; cell biology emphasizing how cells
move, grow, and divide; molecular biology emphasizing the role of
nucleic acids in the storage and expression of genetic information;
and intermediary metabolism emphasizing the degradation and synthesis
of carbohydrates, lipids, and amino acids. Clinical aspects as well
as the regulation and coordination of biologic processes during
the fed and fasted states are emphasized. The workshops introduce
the biochemical basis of common clinical laboratory tests and/or
they illustrate clinical applications of biochemical concepts.
BIOC 1522 Biochemistry II
This course has modules on human nutrition emphasizing the importance
of nutrition in health and preventive medicine; human genetics emphasizing
the inheritance of selected genetic disorders; and tissues and organs
emphasizing the customization and adaptation of biochemical pathways
in specialized cells. Workshops feature a modified problem-based
learning environment. Working in teams, students research various
aspects of a case and orally present their findings to their small
group.