The Integrated Basic Science Sequence (IBSS) is an interdisciplinary sequence of 11 courses that presents the basic science foundation for the practice of dentistry. Didactic lectures covering the normal structure and function of cell and body systems and the relevant immunology, infectious disease and pathological disease processes are supplemented with active learning exercises in a small-group environment. The active learning exercises are designed to apply basic science concepts within a clinical scenario.
Foundations of Cell Function for Dental Students
IBSS 1501 spans three modules that cover cell structure and function; molecular biology of the cell and intermediary metabolism; and relevant cell pathology, and that serve as essential foundational material for the discussion of immunology and body systems which follow in future IBSS courses.Module 1: Cell Biology. The disciplines of histology, biochemistry, and physiology cover general cell structure and function. Topics include cell structure, metabolic fuels, cell transport mechanisms, signal transduction, osmosis and regulation of cell volume, and the cell cycle. Module 2: Molecular Biology and Metabolism. The molecular biology of the cell and intermediary metabolism are covered in this module, which is presented by the Biochemistry faculty. Topics include DNA repair and replication, transcription, translation, and control of gene expression, as well as the processes of carbohydrate, amino acid, triglyceride, lipoprotein and cholesterol synthesis and metabolism. Module 3: Epithelium/Connective Tissue/ Blood. The disciplines of histology, biochemistry, and pathology cover the structure and function of epithelium, connective tissue and blood. Topics include cell and tissue structure and function, hematopoiesis, hemostasis, and mechanisms of cell adaptation, injury and death.
Genetics and Immunology for Dental Students
IBSS 1502 spans two modules that provide an overview of cancer, human genetics, the lymphatic system and immunology.Module 4: Genetics and Cancer. The disciplines of pathology and biochemistry present the fundamentals of human genetics, cancer and relevant genetic disorders. Topics include: molecular biology and pathology of cancer, genetic diseases, autosomal dominant and recessive, sex-linked, mitochondrial and multifactorial genetic disorders and diseases, cytogenetics and an introduction to genetic risk assessment. Module 5: Lymphatics/Immune System. The disciplines of gross anatomy, immunology, and pathology cover the basic structure and function of the lymphatic system and the composition and function of the immune response system. Topics include gross anatomy and histology of the lymphatic system, innate and adaptive immunity, hypersensitivity, inflammation, tissue repair, immune responses to infectious agents, transplantation immunology, autoimmune disease, immunodeficiency disorders and HIV/AIDS.
Infectious Disease, Skin, and Blood Disorders for Dental Students
IBSS 1503 spans two modules that present principles of infectious disease, followed by a discussion of skin and blood disorders and disease.Module 6: Introduction to Infectious Disease. Fundamentals of infectious disease are covered in this module, presented by the microbiology and immunology discipline. Topics include taxonomy, structure, identification and virulence determinants of infectious agents, and principles of infection control, antimicrobial agents and laboratory diagnostics. Module 7: Integument and Blood Disorders. The disciplines of microbiology, biochemistry, and pathology cover mechanisms and the clinical course of relevant integumentary and blood-borne disorders and disease. Topics include bacterial, fungal, viral, and other blood-borne pathogens, dermopathology, anemia, and red and white blood cell disorders.
Neural and Musculoskeletal Systems for Dental Students
IBSS 1504 contains two interdisciplinary modules that cover the structure, function, and relevant pathology of the peripheral nervous system and the musculoskeletal system.Module 8: Nervous System. The disciplines of embryology, gross anatomy, histology, physiology, and pathology cover the basic structure and function of the nervous system with an emphasis on the peripheral nervous system. Topics include the embryological development, histology and structure of the nervous system, physiology of nerve and neuromuscular transmission and peripheral neuromuscular disease. Module 9: Musculoskeletal System. The disciplines of histology, gross anatomy, physiology, biochemistry, and pathology cover the basic principles of musculoskeletal structure and function. Topics include histology of muscle and bone, gross anatomy of the upper extremity, physiology of skeletal muscle, and muscle metabolism. In addition, non-neoplastic bone diseases and diseases of muscle and joints are presented. In addition, there are three 1.5 hour gross anatomy laboratory sessions focused on the upper extremity.
Cardiovascular System for Dental Students
IBSS 1505 presents an interdisciplinary approach to the cardiovascular system.Module 10: Cardiovascular System. The disciplines of histology, gross anatomy, physiology, microbiology and pathology cover the basic structure and function of the cardiovascular system. Topics include gross anatomy and histology of the cardiovascular system, cardiac function, systemic and microcirculatory hemodynamics, control of blood pressure, infective endocarditis and cardiac disease.
Head and Neck Anatomy for Dental Students
IBSS 1506 provides a detailed study of head and neck anatomy relevant to dental medicine.Module 11: Head and Neck Anatomy. Using didactic lectures and dissection laboratory activity, this module covers gross anatomy and function of the head and neck fascia, musculoskeletal, nervous and organ systems. Three-dimensional relationships among anatomical structures are reinforced by in-depth dissections of the head and neck. Emphasis is placed on application of that knowledge to clinical problems.
Respiratory and Urogenital Systems for Dental Students
IBSS 1507 spans two interdisciplinary modules that study the respiratory system and urogenital systems.Module 12: Respiratory System. The disciplines of gross anatomy, histology, biochemistry, physiology, microbiology and pathology cover the structure and function of the respiratory system. Topics include the gross anatomy, histology and biochemistry of the respiratory system, pulmonary mechanics, gas exchange, and control of ventilation, as well as infections and diseases of the respiratory system. Module 13: Urogenital System. The disciplines of gross anatomy, histology, physiology, microbiology and pathology cover the structure and function of the urinary system. Topics include the gross anatomy and histology of the reproductive and urinary systems, renal and acid base physiology, sexually transmitted disease and common pathologies of the urinary system.
Clinical Neuroscience for Dental Students
IBSS 1608 presents an interdisciplinary approach to clinical neuroscience with an emphasis on cranial nerve distribution and function.Module 14: Clinical Neuroscience. The disciplines of anatomy, physiology, microbiology and pathology cover the gross anatomy and function of the central nervous system (CNS). Topics include central neuroanatomy with emphasis on cranial nerve distribution and function, somatosensory function, special senses, CNS infectious disease, the motor system, higher cortical function and relevant CNS pathology. Clinical case studies are incorporated into the module to provide practice in applying basic science knowledge in clinical problem-solving scenarios.
Endocrine and Reproductive Systems for Dental Students
IBSS 1609 spans two interdisciplinary modules that provide a basic overview of the endocrine system, human reproduction, somatic growth and aging.Module 15: Endocrine Systems. The disciplines of gross anatomy, histology, physiology, microbiology, and pathology cover the basic structure and function of the endocrine system. Topics include gross anatomy, histology and physiology of the endocrine system and common disorders and diseases of the endocrine system, with an emphasis on diabetes. Module 16: Reproduction. The disciplines of anatomy, physiology and pathology survey the structure, function and pathology of the male and female reproductive systems. In addition, the physiology of somatic growth and development, pregnancy, menopause and aging are presented.
Gastrointestinal System for Dental Students
IBSS 1610 presents an interdisciplinary approach to the gastrointestinal system.Module 17: Gastrointestinal System. The disciplines of histology, gross anatomy, physiology, microbiology and pathology cover gastric, intestinal, and hepatic and pancreatic structure, function and common pathology. Additional topics include chewing, swallowing and esophageal function, gastric infections, hepatitis and infectious diarrheas. This course will conclude in the 4th week of the Fall Quarter Y-2.
An American Family: Clinical Integration Course
In this capstone course in the basic science curriculum, students will apply knowledge and concepts learned previously in the basic sciences to real-life clinical and behavioral situations. By focusing on “An American Family”, students will learn to apply these concepts across generations from geriatric (the grandparents), middle-aged (the parents), and pediatric (infant, child and younger-adult) patients. IBSS 1620 is taught almost entirely using team-based learning (TBL). In TBL, students work in their team of 5-7 individuals during three class sessions and one team discussion per week (total of 6 hours/week). Clinical problems will be introduced biweekly, researched and studied by the teams. Each in-class session is facilitated by one or more instructors from dental medicine and the basic science disciplines. This course begins Winter Quarter of Year 2 and continues through the Spring Quarter.
Pharmacology for Dental Students
The various classes of drugs will be considered on the basis of both therapeutic use and organ systems. Drug classes most relevant to general dental practice, such as analgesics, drugs that affect the autonomic nervous system, sedatives, anxiolytics and muscle relaxants, local and general anesthetics, and antimicrobial therapy are considered in detail. Students will receive basic instruction on additional drug classes used in the treatment of allergies and asthma, osteoporosis, and cardiovascular, metabolic, gastrointestinal, psychiatric and immune system disorders. In addition, there is coverage of related topics such as general principles of drug action, pharmacokinetics, toxicology, and drugs of abuse. This course begins in the 5th week of the Fall Quarter Y-2 (20 hours) and continues for an additional 30 hours in the Winter Quarter Y-2. This course is taught during the Fall and Winter quarters with a single grade given at the completion of the course.