Ira Sigar, Ph.D.

Associate Professor
Downers Grove, IL

Home / Academics / Ira Sigar, Ph.D.

Associate Professor

Downers Grove, IL

Chicago College of Osteopathic Medicine
College of Dental Medicine-Illinois
College of Graduate Studies - IL

Microbiology & Immunology

Biomedical Sciences (M.A.)
Biomedical Sciences (M.B.S.)
Dental Medicine
Osteopathic Medicine

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Illinois Institute of Technology
IL. | 2005 | Ph.D.
Illinois Institute of Technology
IL. | 1994 | M.S.
University of Indonesia
Jakarta-Indonesia | 1991 | B.S.


Sigar IM, Kaminski A, Ito B, Christoffersen-Cebi J, Vidovich A, Macarulay C, Rowan E, Plotkin BJ. Comparison of In Vitro Chlamydia muridarum Infection Under Aerobic and Anaerobic Conditions. Curr Microbiol. 2020 Aug;77(8):1580-1589. doi: 10.1007/s00284-020-01966-9. Epub 2020 Apr 6. PubMed PMID: 32253468

Plotkin BJ, Sigar IM, Kaminski A, Kreamer J, Ito B, and Kacmar J. Kinetics of Candida albicans and Staphylococcus aureus Biofilm Initiation on Herpes Simplex Virus (HSV-1 and HSV-2) Infected Cells. Advances in Microbiol. 2020; (10): 583-598. doi: 10.4236/aim.2020.1011043.

Prozialeck WC, Edwards JR, Lamar PC, Plotkin BJ, Sigar IM, Grundmann O+, Veltri CA+. Evaluation of the Mitragynine Content, Levels of Toxic Metals and the Presence of Microbes in Kratom Products Purchased in the Western Suburbs of Chicago. Int J Environ Res Public Health. 2020 Jul 30;17(15):5512. doi: 10.3390/ijerph17155512. PMID: 32751712; PMCID: PMC7432033.

Wang SK, Gilchrist A, Loukitcheva A, Plotkin BJ, Sigar IM, Gross AE, O'Donnell JN, Pettit N, Buros A, O'Driscoll T, Rhodes NJ, Bethel C, Segreti J, Charnot-Katsikas A, Singh K, Scheetz MH. Prevalence of a Cefazolin Inoculum Effect Associated with blaZ Gene Types among Methicillin-Susceptible Staphylococcus aureus Isolates from Four Major Medical Centers in Chicago. Antimicrob Agents Chemother. 2018 Aug;62(8). doi: 10.1128/AAC.00382-18. PubMed PMID: 29891607; PubMed Central PMCID: PMC6105856

Plotkin BJ, Sigar IM, Swartzendruber JA, Kaminski A. Anaerobic Growth and Maintenance of Mammalian Cell Lines. J Vis Exp. 2018 Jul 21;(137). doi: 10.3791/58049. PubMed PMID: 30080196; PubMed Central PMCID: PMC6126527.

Plotkin BJ, Sigar IM, Swartzendruber JA, Kaminski A, Davis J. Differential expression of cytokines and receptor expression during anoxic growth. BMC Res Notes. 2018 Jun 25;11(1):406. doi: 10.1186/s13104-018-3520-5. PubMed PMID: 29941048; PubMed Central PMCID: PMC6019713.

Sigar IM, Schripsema JH, Kelly KA, Murthy AK, Manam S, Ramsey KH. Elimination of Mycoplasma contamination in Chlamydia stocks as a result of in vivo passage or plaque isolation. BMC Res Notes. 2018 Jun 7;11(1):361. doi: 10.1186/s13104-018-3455-x. PubMed PMID: 29880030; PubMed Central PMCID: PMC5992720.

Plotkin BJ, Davis JW, Strizzi L, Lee P, Christoffersen-Cebi J, Kacmar J, Rivero OJ, Elsayed N, Zanghi N, Ito B, Sigar IMA method for the long-term cultivation of mammalian cells in the absence of oxygen: Characterization of cell replication, hypoxia-inducible factor expression and reactive oxygen species production. Tissue Cell. 2018 Feb;50:59-68. doi: 10.1016/j.tice.2017.12.004. Epub 2017 Dec 15. PubMed PMID: 29429519.