Graduate and undergraduate trainees are italicized, *denotes corresponding author, +denotes shared first authorship
Prieur EAK, Pjetri E, Ziesel S, Jadavji NM*. (2017) BHMT-deficiency results in brain atrophy and impairs memory in mice. Applied Physiology, Nutrition, and Metabolism, 42:1228-1231. PMID: 28715642.
Jadavji NM*, Wieske F, Dirgnal U, Winter C. (2015) Methylenetetrahydrfolate reductase deficiency alters levels of monoamine neurotransmitters, glutamate and gamma aminobutyric acid in brain tissue. Molecular Genetics and Metabolism and Genetics Reports, 3:1-4. PMID: 26937386.
Jadavji NM, Bahous R, Deng L, Wang XL, Malysheva O, Caudill MA, Bedell BJ, Rozen R. (2014) A mouse model for genetic variation in methionine synthase reductase exhibits mild hyperhomocysteinemia, short-term memory impairment and biochemical changes in hippocampus. Biochemical Journal, 461:205-12. PMID: 24800750.
Jadavji NM, Deng L, Leclerc D, Malysheva O, Caudill MA, Bedell BJ, Rozen R. (2012) Methylenetetrahydrofolate reductase deficiency in mice impairs motor and cognitive function, with morphological and neurobiochemical changes in cerebellum and hippocampus. Molecular Genetics and Metabolism, 106:149-159. PMID: 22521626.
Maternal nutrition contributions on offspring neurological health
Al Rubaye H, Adamson C, Jadavji NM*. (2020) The role of maternal diet on offspring gut microbiota development. Journal of Neuroscience Research. PMID 32112450
Murray LK, Smith MJ, Jadavji NM. (2018) Maternal over supplementation with folic acid and its impact on neurodevelopment of offspring. Nutrition Reviews. 76:708-721. PMID: 30010929.
Jadavji NM*. (2017) The integrated stress response is not a target for diffuse white matter injury in premature infants. Journal of Neuroscience, 37: 11772-1173. PMID: 29212946.
Bahous R, Jadavji NM, Deng L, Cosin-Tomas M, Lu J, Malysheva O, Leung KY, Ho MK, Pallas M, Kaliman P, Greene NDE, Bedell BJ, Caudill MA, Rozen R. (2017) High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring. Human Molecular Genetics, 26:888-900. PMID: 28069796.
Jadavji NM, Malysheva O, Caudill MA, Rozen R. (2015) MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in hippocampus in wild-type offspring. Neuroscience, 300: 1-9. PMID: 25956258.
Jadavji NM*, Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Smith PD (2019) One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. Neurobiology of disease. 132, 104613. PMID: 3152543
Jadavji NM*, Emmerson JT, Shanmugalingam U, Willmore WG, MacFarlane AJ, Smith P. (2018) MTHFR-deficiency increases vulnerability to stroke: in vitro and in vivo. Experimental Neurology, 309:14-22. PMID: 30055159.
Emmerson JT, Murray LK, Jadavji NM*. (2017) Impact of one-carbon metabolism on neural regeneration in the central nervous system. Neural Regeneration,12: 1-2. (invited). PMID: 28852387.
Jadavji NM*, Emmerson JE, Willmore WG, MacFarlane AJ, Smith PD. (2017) B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke. Neurobiology of disease, 103:89-100. PMID: 28396257.
Dam K, Füchtemeier M, Farr TD, Boehm-Strum P, Foddis M, Dirnagl U, Jadavji NM*. (2017) Deficiencies in methylenetetrahydrofolate reductase and dietary folic acid alter choline metabolism during chronic hypoperfusion. Behavioral Brain Research, 321:201-208. PMID: 28087280.
Jadavji NM*, Farr TD, Lips L, Khalil A, Boehm-Sturm P, Harms C, Foddis M, Füchtemeier M, Dirnagl. (2015) Elevated levels of homocysteine, deficiencies in folic acid and uracil-DNA glycosylase impair learning in a mouse model of vascular cognitive impairment. Behavioural Brain Research, 283: 215-226. PMID: 2565513.
Murray LK, Jadavji NM*. (2019). The role of B-vitamin metabolism in Parkinson’s disease onset, pathology, and mechanisms. Nutrition Research Reviews, 32 (2), 218-230. PMID: 31303188
Jadavji NM*, Murray LK, Emmerson JT, Rudyk CA, Hayley S, Smith PD. (2019) A genetic deficiency in one-carbon metabolism increases oxidative stress in a mouse mode of Parkinson’s disease. Toxicological Sciences. 169:25-33. PMID: 30726997.
Jadavji NM, Metz GA. (2009) Both pre- and post-treatment with experiential therapy is beneficial in 6-OHDA dopamine-depleted rat. Neuroscience, 158:373-86. PMID: 19032978.
Jadavji NM, Kolb B and Metz GA. (2006) Enriched environment improves motor function in intact and dopamine-depleted rats: implications for Parkinson’s disease. Neuroscience, 140: 1127-1138. (IF = 3.327). PMID: 1667892.