Thu Huynh, Ph.D.

Assistant Professor
Glendale, AZ

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Title
Assistant Professor

Campus
Glendale, AZ

College
College of Graduate Studies - AZ
Arizona College of Osteopathic Medicine

Department
Biochemistry and Molecular Genetics

Program
Dental Medicine
Nurse Anesthesia Practice (M.S.)
Optometry
Osteopathic Medicine
Physician Assistant Studies
Podiatric Medicine

Call My
Office

623-537-3703

Send Me
a Message

thuynh@midwestern.edu

Education

New York University | 2015 | Ph.D.
University of Arizona | 2007 | B.S.

Publications

Huynh TN, Krigbaum AM, Hanna JJ, Conrad CD. Sex differences and phase of light cycle modify chronic stress effects on anxiety and depressive-like behavior. Behavioral Brain Research. 2011 Sep 12;222(1):212-22. doi: 10.1016/j.bbr.2011.03.038. 
 

Conrad CD, McLaughlin KJ, Huynh TN, El-Ashmawy M, Sparks M. Chronic stress and a cyclic regimen of estradiol administration separately facilitate spatial memory: relationship with hippocampal CA1 spine density and dendritic complexity. Behavioral Neuroscience. 2012 Feb;126(1):142-56. doi: 10.1037/a0025770. 
 

Santini E, Huynh TN, MacAskill AF, Carter AG, Pierre P, Ruggero D, Kaphzan H, Klann E. Exaggerated translation causes synaptic and behavioural aberrations associated with autism. Nature. 2013 Jan 17;493(7432):411-5. doi: 10.1038/nature11782. 
 

Santini E, Huynh TN, Klann E. Mechanisms of translation control underlying long-lasting synaptic plasticity and the consolidation of long-term memory. Progress in Molecular Biology Translational Science. 2014;122:131-67. doi: 10.1016/B978-0-12-420170-5.00005-2. 
 

Huynh TN, Santini E, Klann E. Requirement of Mammalian target of rapamycin complex 1 downstream effectors in cued fear memory reconsolidation and its persistence. Journal of Neuroscience. 2014 Jul 2;34(27):9034-9. doi: 10.1523/JNEUROSCI.0878-14.2014. 
 

Huynh TN, Shah M, Koo SY, Faraud KS, Santini E, Klann E. eIF4E/Fmr1 double mutant mice display cognitive impairment in addition to ASD-like behaviors. Neurobiology of Disease. 2015 Nov;83:67-74. doi: 10.1016/j.nbd.2015.08.016. 
 

Santini E, Huynh TN, Longo F, Koo SY, Mojica E, D'Andrea L, Bagni C, Klann E. Reducing eIF4E-eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice. Science Signaling. 2017 Nov 7;10(504). doi: 10.1126/scisignal.aan0665.
 

Huynh TN, Santini E, Mojica E, Fink AE, Hall BS, Fetcho RN, Grosenick L, Deisseroth K, LeDoux JE, Liston C, Klann E. Activation of a novel p70 S6 kinase 1-dependent intracellular cascade in the basolateral nucleus of the amygdala is required for the acquisition of extinction memory. Molecular Psychiatry. 2018 Jun;23(6):1394-1401. doi: 10.1038/mp.2017.99. 
 

Moda-Sava RN, Murdock MH, Parekh PK, Fetcho RN, Huang BS, Huynh TN, Witztum J, Shaver DC, Rosenthal DL, Alway EJ, Lopez K, Meng Y, Nellissen L, Grosenick L, Milner TA, Deisseroth K, Bito H, Kasai H, Liston C. Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation. Science. 2019 Apr 12;364(6436). doi: 10.1126/science.aat8078.

 

More Information

www.huynhlab.org