Ashlesh Murthy, M.D., Ph.D.

Associate Dean for Research


Ashlesh K. Murthy, MD, PhDCollege of Veterinary Medicine
Associate Dean for Research
Department of Pathology and Population Medicine
Midwestern University

Cactus Wren 332-E
19555 59th Ave.
Glendale, AZ 85308

Office: 623-537-3299
e-mail: mailto:amurth@midwestern.edu

 

EDUCATION

M.D.           Bachelor of Medicine and Surgery    Bangalore Medical College, India    1999
Ph.D.          Cell and Molecular Biology               The University of Texas                2006

RESEARCH SUMMARY

Approximately 25% of deaths worldwide are caused by infectious diseases, with a substantial contribution from infections in mucosal compartments.  My laboratory is interested in the general areas of immunity against bacterial pathogens that infect the ocular, respiratory, gastrointestinal, and genitourinary mucosa.  Some model organisms used in the laboratory include Chlamydia trachomatis and Chlamydia pneumoniae, which induce infertility in females and cardiovascular diseases, respectively.

Immune responses in general, and specifically at mucosal surfaces, have the ability to kill pathogens and clear infection.  Being potently inflammatory, sometimes immune responses also cause undesirable collateral damage to surrounding tissues.

 We aim to understand:

A variety of contemporary in vitro and in vivo experimental approaches including cell and molecular biology, immunology, and biochemistry techniques, and small animal models are used.  We utilize the insights gained from such research in development of safe and efficacious vaccines against infections that cause significant morbidity in human populations.

PUBLICATIONS

http://www.ncbi.nlm.nih.gov/pubmed/?term=Ashlesh+Murthy

ACTIVE EXTRAMURAL GRANT FUNDING

CURRENT TEACHING ACTIVITIES