Michael H. Jaffe, DVM, MS, DACVS

Assistant Professor Small Animal Surgery

Midwestern University
College of Veterinary Medicine
Department of Small Animal Surgery
323-G Companion Animal Clinic
19555 59th Ave.
Glendale, AZ 85308

Office: (623) 806-7480
e-mail: mjaffe@midwestern.edu


B.S. Zoology University of Massachusetts 1986
D.V.M Vet Med University of Missouri 1991
M.S Vet Clin Sci Louisiana State University 1999
DACVS 2002


Laser tissue welding is a suture-less surgical method for the anastomosis of incised tissue. This is achieved by tissue absorption of laser light converted to heat energy, resulting in deformation of tissue proteins at ~60oC and their eventual fusion upon cooling. Fusion of photo-thermally altered collagen via covalent and electrostatic interactions is the mechanisms by which tissue welding results. Preliminary data using ex vivo porcine intestine showed that a plasmonic nanocomposite, generated from elastin-like polypeptides cross linked with gold nanorods, could be used to weld intestinal tissue subsequent to exposure to a near-infrared laser. Pressure testing of the welded tissue following treatment demonstrated decreased anastomotic leakage. My current research involves the assessment of healing in a mouse colotomy model following laser tissue welding with a gold nanorod-collagen composite following treatment with a near infra-red laser.

Research project

Since 2014, I have been be working in collaboration with the department of Chemical Engineering, Arizona State University and the Department of Surgery, Mayo Clinic Scottsdale, AZ in the evaluation of a gold nano-rod with collagen to be used for laser tissue welding. The nano-composite is placed in vivo at the site of a colotomy in mice. The tissue is then treated with a near infra-red laser to create the tissue weld. After 7 days the colon sections are evaluated histologically for healing, gross signs of peritonitis, tissue bursting pressure is tested and leakage from the colotomy site is assessed.

Selected Publications

Gold Nanorod-Collagen Nanocomposites as Photothermal Nanosolders for Laser Welding of Ruptured Porcine Intestines Russell Urie, Sana Quraishi, Michael Jaffe, Kaushal Reg. ACS Biomater. Sci. Eng., 2015, 1 (9), pp 805-815.

Decreased surgical time with a vessel sealing device versus a surgical stapler in performance of canine splenectomy. Monarski CJ, Jaffe MH, Kass PH. J Am Anim Hosp Assoc. 2014 Jan-Feb;50(1):42-5. doi: 10.5326/JAAHA-MS-5981.

Evaluation of two novel self-anchoring barbed sutures in a prophylactic laparoscopic gastropexy compared with intracorporeal tied knots. Spah CE, Elkins AD, Wehrenberg A, Jaffe MH, Baird DK, Naughton JF, Payton ME. Vet Surg. 2013 Nov;42(8):932-42. doi: 10.1111/j.1532-950X.2013.12043.x.