Najmeh Hoseini, PT, PhD

Assistant Professor


Midwestern University 
College of Health Sciences Physical Therapy Program
Glendale Hall 327-15
19555 N. 59 Ave.
Glendale, AZ  38305

Office: (623) 572 3933
e-mail: nhosei@midwestern.edu

EDUCATION

B.S. Physical Therapy Iran University of Medical Sciences (Iran) 2003
M.S. Physical Therapy Iran University of Medical Sciences (Iran) 2006
Ph.D. Human Performance Indiana University (Bloomington) 2015

RESEARCH INTERESTS

The effect of brain stimulation on upper extremity function in patients with stroke 

According to the American Heart Association, there are 795,000 stroke survivals each year in the United States which causes both a physical and a financial burden on individuals' families and society as a whole. Upper limb, specifically hand function, impairment is one of the most common motor complications in this group of patients. I am interested in investigating a new therapeutic combination of central and peripheral electrical stimulation in order to improve the manual function in patients with stroke.

Transcranial direct current stimulation (tDCS), involves stimulation of the central nervous system. Weak direct currents can be applied non-invasively, transcranially and painlessly. This noninvasive emerging technique has been found helpful in facilitating the treatment in neurologic disorders like stroke.  Compared to motor practice as the only method of treatment for a functional impairment post-stroke, combining tDCS with motor practice and/or electrical simulation of involved muscles may have certain advantages over motor practice.  For example, wrist and fingers extension is usually affected by stroke and tDCS over the motor representations of these areas in the brain, may be a viable treatment.
Previous research has shown that Functional electrical stimulation (FES) has a role in functional improvement in manual motor function in stroke patients. Previous research has shown that transcranial direct current stimulation (tDCS) can be used as a facilitation method in addition to the other rehabilitation techniques for enhancing neuroplasticity. Previously we found significant effect on manual dexterity in healthy subjects when using a combined method of tDCS with electrical simulation of hand muscles (Hoseini, 2016).

RESEARCH PROJECTS

In my current research, we examin the combination effect of functional electrical simulation (FES) on arm muscles combined with tDCS on sensorimotor cortex in patients with stroke to investigate the short term and long term functional consequences of this intervention. 

SELECTED PUBLICATIONS

Combined motor point associative stimulation (MPAS) and transcranial direct current stimulation (tDCS) improves plateaued manual dexterity performance

Hoseini N, Munoz-Rubke F, Wan HY, Block HJ. Neurosci Lett. 2016 Sep 21;633:134-140.

doi: 10.1016/j.neulet.2016.09.034

Adaptive Staircase Measurement of Hand Proprioception. 

Hoseini N, Sexton BM, Kurtz K, Liu Y, Block HJ.PLoS One. 2015 Aug 14;10(8):e0135757.
doi: 10.1371/journal.pone.0135757. eCollection 2015.

The effect of operant-conditioning balance training on the down-regulation of spinal H-reflexes in a spastic patient.
Hoseini N, Koceja DM, Riley ZA.Neurosci Lett. 2011 Oct 24;504(2):112-4.
doi: 10.1016/j.neulet.2011.09.009. Epub 2011 Sep 16.

CONFERENCE PAPERS:

Anodal and cathodal tDCS as a therapy for fine motor skill impairment in Autism Spectrum Disorder
Susannah M. Owen · Najmeh Hoseini · Georgia Frey · Hannah J. Block

The effect of motor point associative stimulation (MPAS) and transcranial direct current stimulation (tDCS) on sensorimotor neuroplasticity and dexterity of hand
Najmeh Hoseini · Hsuan-Yu Wan · Felipe Munoz · Hannah J Block